The Capto SP ImpRes Ion Exchange Resin, 25 mL (17546810) is a strong cation exchange chromatography resin for intermediate purification and polishing of biomolecules. It combines a high-flow agarose base matrix with a small approximately 40 µm bead size, supporting high resolution, high throughput, and robust protein purification workflows.
Key Features
- 25 mL bulk resin format, supplied as Capto SP ImpRes resin for method development and polishing workflows
- Strong cation exchange chemistry, using a sulfopropyl functional group for ion exchange chromatography
- High-flow agarose matrix, designed to provide good pressure-flow properties for high-throughput processing
- Small bead size for high resolution, with an average particle size of approximately 40 µm
- High dynamic binding capacity, with greater than 70 mg lysozyme/mL resin and greater than 95 mg BSA/mL resin under specified test conditions
- Useful operating flow velocity, at least 220 cm/h in a 1 m diameter column with 20 cm bed height at 20°C under stated conditions
- Broad pH stability, with working pH stability from 4 to 12 and cleaning pH stability from 3 to 14
- Good chemical stability, stable with commonly used aqueous buffers, 1 M sodium hydroxide, 8 M urea, 6 M guanidine hydrochloride, 30% isopropanol, and 70% ethanol
Benefits
- Supports reliable polishing steps where both high binding capacity and high resolution are important.
- Helps improve process productivity by combining small bead resolution with high-flow pressure performance.
- Provides a scalable resin option for laboratories developing industrial protein purification workflows.
- Supports cleaning and sanitisation conditions commonly used in downstream chromatography processes.
Why Choose the Capto SP ImpRes Ion Exchange Resin, 25 mL (17546810)?
The Capto SP ImpRes Ion Exchange Resin, 25 mL (17546810) is a suitable choice for laboratories requiring a strong cation exchanger for high-resolution intermediate purification and polishing. John Morris Group supplies Cytiva chromatography resins to Australian laboratories, helping users source verified consumables for downstream purification and process development.
