The HiTrap Capto Adhere Column, 1 x 1 mL (29400456) is a prepacked chromatography column containing Capto adhere, a multimodal BioProcess ion exchange resin. It is designed for contaminant removal in post-protein A purification, including monoclonal antibody purification workflows.
Key Features
- Prepacked 1 mL HiTrap column, supplied as one 1 x 1 mL column for convenient screening and process development
- Strong anion exchanger with multimodal functionality, giving different selectivity compared with traditional anion exchangers
- Designed for post-protein A purification, supporting removal of contaminants after protein A capture steps
- Supports flowthrough contaminant removal, where monoclonal antibodies pass through while contaminants are adsorbed
- Compact column dimensions, with a 7 mm inner diameter and 25 mm bed height
- Flow rate below 4 mL/min, with a maximum pressure rating of 5 bar
- Capto matrix with N-benzyl methyl ethanolamine ligand, matching the specified resin chemistry for this column
- Supplied in 20% ethanol, with storage guidance of 4°C to 30°C
Benefits
- Helps simplify early screening and process development using a ready-to-use prepacked column format.
- Supports polishing workflows where leached protein A, aggregates, host cell proteins, nucleic acids and viruses need to be reduced.
- Provides a practical column format for evaluating Capto adhere resin performance before process scale-up.
- Supports efficient flowthrough purification strategies in monoclonal antibody workflows.
Why Choose the HiTrap Capto Adhere Column, 1 x 1 mL (29400456)?
The HiTrap Capto Adhere Column, 1 x 1 mL (29400456) provides a verified prepacked column option for post-protein A contaminant removal studies. John Morris Group can help confirm availability and support the selection of compatible chromatography consumables for your purification workflow.
