The Capto Core 700 Multimodal Resin, 100 mL (17548102) is a multimodal chromatography resin for intermediate purification and polishing of viruses and other large biomolecules. It uses core bead technology with an inactive shell and ligand-activated core, combining size exclusion and binding chromatography in one flowthrough purification resin.
Key Features
- 100 mL bulk resin format, supplied for packing into suitable chromatography columns during multimodal purification development or process work
- Dual-function core bead technology, combining size separation and binding chromatography in one resin
- Mr 700 000 molecular weight cut-off, excluding large target molecules from the bead core while smaller impurities enter and bind
- Multimodal octylamine ligand, providing hydrophobic and positively charged binding interactions inside the bead core
- Highly cross-linked agarose matrix, designed for high-flow packed-bed chromatography with low back pressure
- 85 µm average particle size, supporting high volume throughput in intermediate purification and polishing workflows
- High operating flow capability, with maximum flow velocity of 500 cm/h at 20 cm bed height and below 2 bar pressure
- Broad cleaning and operating window, with operational pH stability of 3 to 13 and CIP pH stability of 3 to 14
Benefits
- Helps capture smaller contaminants while allowing larger targets such as viruses and large biomolecules to pass in the flowthrough.
- Supports faster processing than conventional size exclusion chromatography by allowing higher sample loads and flow rates.
- Provides a broad operating window for robust method development across relevant pH and salt conditions.
- Can help improve process productivity in intermediate purification and polishing workflows where SEC would be a bottleneck.
Why Choose the Capto Core 700 Multimodal Resin, 100 mL (17548102)?
Choose the Capto Core 700 Multimodal Resin, 100 mL (17548102) when you need a flowthrough multimodal resin for polishing viruses or other large biomolecules while binding smaller impurities. John Morris Group supplies Cytiva chromatography consumables for Australian laboratories and can help confirm suitability for your purification workflow.
