Capto adhere ImpRes Resin, 100 mL (17371502) is a multimodal strong anion exchange chromatography resin for high-resolution monoclonal antibody polishing. It is designed for second or third purification steps downstream of protein A capture, supporting impurity removal in bind/elute or flowthrough polishing workflows.
Key Features
- Multimodal strong anion exchange ligand, enabling ionic, hydrophobic and hydrogen bonding interactions during purification
- High-flow agarose matrix, supporting good pressure/flow properties for chromatography polishing processes
- Small 36-44 µm average particle size, optimised for high-resolution polishing compared with larger bead formats
- 45-85 mg mAb/mL binding capacity, measured at 4-5 min residence time and approximately pH 8
- Broad pH operating range, with a working range of pH 3-12 and CIP range of pH 2-14
- Defined pressure/flow specification, rated at 300 kPa at minimum 220 cm/h using a 1 m diameter column with 20 cm bed height
- Stable storage format, supplied as 100 mL resin with storage conditions of 4°C to 30°C in 20% ethanol
Note: Avoid using oxidizing agents and anionic detergents with this resin.
Benefits
- Supports effective removal of aggregates, host cell proteins, leached protein A, DNA and viruses from mAb processes.
- Helps improve polishing resolution where charged variants and closely related impurities need to be separated.
- Can be used in bind/elute or flowthrough mode to suit different purification strategies.
- Provides a scalable resin format for process development and downstream purification workflows.
Why Choose the Capto adhere ImpRes Resin, 100 mL (17371502)?
Capto adhere ImpRes Resin, 100 mL (17371502) combines a high-flow agarose base matrix with a multimodal anion exchange ligand for demanding mAb polishing applications. John Morris Group supplies this Cytiva resin for Australian laboratories and bioprocess teams requiring verified chromatography consumables.
