The CEM MultiPep 2™ system (formerly MultiPep RSi) is an automated multiple peptide synthesizer controlled by a pipetting robot and operated using dedicated Windows-based software. The synthesis scale on resin ranges from 1 to 500 µmol depending on the synthesis module used. This system also supports automated synthesis of membrane-bound peptide arrays. It is optimized for Fmoc-based peptide synthesis with activation by HBTU/NMM or similar protocols. A single probe picks up reagents and distributes them precisely into the wells of the reaction module. Amino acid solutions are activated by adding activator and base in individual mixing vials before distribution. Reagents remain in the reaction wells by surface tension and are removed by vacuum applied through the bottom of the reaction module via an included pump. The MultiPep 2™ is delivered with Windows-based software and a PC for efficient operation.
Product Features
- Automated peptide synthesizer with precise pipetting robot control
- Synthesis scale from 1 to 500 µmol based on selected modules
- Supports automated synthesis of membrane-bound peptide arrays
- Optimized for Fmoc chemistry using HBTU/NMM activation
- Single probe accurately distributes reagents into wells
- Individual mixing vials activate amino acid solutions prior to use
- Vacuum extraction system ensures efficient removal of reagents
- Delivered with Windows software and PC for streamlined control
- Upgrade Kit: 48 Column Synthesis with Shaker — synthesizes up to 48 peptides in parallel using individual columns (2-, 5-, 10-, and 20-mL) at 5–500 µmol scale
- Upgrade Kit: SPOT Synthesis (Four Membranes) — enables synthesis of up to 2400 peptides on four cellulose membranes
- Upgrade Kit: CelluSpots™ (Two 384-Well Plates) — synthesizes peptide-cellulose conjugate arrays on planar surfaces such as glass slides; up to 768 peptides synthesized in parallel
NOTE: This system requires at least one upgrade kit for peptide synthesis.
What's Included
- MultiPep 2™ system with Windows-based control software and PC
- Integrated vacuum pump for reagent extraction
Benefits
- Enables scalable, high-throughput peptide synthesis with modular upgrades
- Supports membrane-bound peptide array production for research flexibility
- Accurate reagent handling reduces error and improves synthesis quality
- Minimizes manual labor through full automation and software control
- Modular design allows customization to meet varied synthesis needs
Why Choose the CEM MultiPep 2™?
The CEM MultiPep 2™ system is the ideal solution for labs requiring flexible, automated peptide synthesis with high throughput and precision. Its advanced pipetting technology combined with modular upgrade kits supports diverse applications from routine synthesis to large peptide array production, making it a versatile asset in proteomics and peptide research.