Capto Butyl ImpRes Resin, 100 mL (17371902) is a hydrophobic interaction chromatography resin for intermediate purification and polishing steps in downstream protein purification. It uses a high-flow agarose matrix with a butyl ligand and a 40 µm average particle size to support high-resolution HIC separations.
Key Features
- Hydrophobic interaction chromatography resin, designed for intermediate and polishing steps in downstream purification workflows
- High-flow agarose matrix, supporting good pressure and flow properties for process chromatography
- Butyl ligand chemistry, providing HIC selectivity for proteins and other hydrophobic biomolecules
- 40 µm average particle size, supporting high-resolution polishing compared with larger bead HIC resins
- 37 mg BSA/mL binding capacity, measured at 10% breakthrough and 4 min residence time
- Defined hydrophobicity profile, with 52 to 58 min retention of alpha-chymotrypsinogen under Cytiva test conditions
- Broad pH stability, with operational stability from pH 3 to 13 and CIP stability from pH 2 to 14
- Stable 100 mL bulk format, supplied for storage in 20% ethanol at 4°C to 30°C
Benefits
- Supports high-resolution HIC polishing where selectivity and impurity removal are important.
- Provides a useful option after ion exchange or other high-salt purification steps.
- Helps process teams screen and optimise hydrophobic interaction conditions for proteins and biomolecules.
- Combines smaller bead size with Capto platform pressure and flow properties for efficient downstream processing.
Why Choose the Capto Butyl ImpRes Resin, 100 mL (17371902)?
Capto Butyl ImpRes Resin, 100 mL (17371902) gives laboratories a high-resolution HIC resin format for intermediate purification and polishing development. John Morris Group supplies this Cytiva resin for Australian laboratories requiring verified chromatography consumables for downstream process optimisation.
