The HiScreen MabSelect Xtra 4.7 mL Column (28926976) is a prepacked protein A affinity chromatography column for process development and parameter screening in monoclonal antibody capture workflows. The column is packed with MabSelect Xtra resin and has a 4.7 mL bed volume with 0.77 × 10 cm column dimensions.
Key Features
- Prepacked MabSelect Xtra format, supplied as a ready-to-use HiScreen column for protein A affinity chromatography
- 4.7 mL process development scale, helping reduce sample and buffer consumption during method optimisation
- 10 cm bed height, designed to support parameter screening and linear scale-up using the same linear flow velocity
- High-capacity protein A resin, with approximately 40 mg human IgG/mL resin dynamic binding capacity under Cytiva stated test conditions
- Defined loading and flow guidance, with a typical loading range of 5 to 200 mg human IgG per column and 1.2 to 2.3 mL/min recommended to maximum flow rate
- Robust column hardware, made from biocompatible polypropylene with an 8 bar hardware pressure limit
- System-friendly operation, suitable for use with peristaltic pumps or chromatography systems such as ÄKTA systems
Benefits
- Supports efficient optimisation of monoclonal antibody capture conditions before scale-up.
- Allows process fluid velocities to be assessed in a small, prepacked column format.
- Helps generate reproducible process development data using BioProcess resin in a standard HiScreen column.
- Provides a convenient bridge between high-throughput screening and larger chromatography column formats.
Why Choose the HiScreen MabSelect Xtra 4.7 mL Column (28926976)?
The HiScreen MabSelect Xtra 4.7 mL Column (28926976) is suited to method optimisation and parameter screening for monoclonal antibody capture using MabSelect Xtra resin. John Morris Group supplies Cytiva chromatography consumables to support reliable process development workflows across Australian laboratories.
