The MabSelect SuRe 70 Protein A Resin, 200 mL (17542402) is a bulk protein A affinity chromatography resin for capture of monoclonal antibodies. It is designed for high dynamic binding capacity and cost-efficient mAb capture, particularly where strong productivity is needed at shorter residence times and low resin utilisation.
Key Features
- Bulk resin format, supplied as a 200 mL pack for flexible column packing and process development
- High dynamic binding capacity, with DBC above 70 mg mAb/mL resin at 6 min residence time
- Strong short-residence-time performance, with DBC above 65 mg mAb/mL resin at 4 min residence time
- Highly cross-linked agarose matrix, using a spherical high-flow base matrix for mAb capture workflows
- Alkali-stable protein A-derived ligand, produced in E. coli and coupled by single-point attachment
- 50 µm median particle size, supporting efficient mass transfer and packed-bed chromatography performance
- Recommended maximum flow velocity up to 400 cm/h, based on operation at 10 cm bed height
- Robust alkaline cleaning compatibility, with CIP stability in 0.1 to 0.5 M NaOH
Benefits
- Supports cost-efficient capture of monoclonal antibodies where a limited number of resin cycles is expected.
- Helps improve resin utilisation through high binding capacity at practical residence times.
- Enables productive short-bed-height workflows, including rapid cycling chromatography applications.
- Supports robust cleaning strategies that help reduce bioburden risk during mAb processing.
- Provides a scalable bulk resin format for moving from process development toward clinical or commercial-scale production.
Why Choose the MabSelect SuRe 70 Protein A Resin, 200 mL (17542402)?
The MabSelect SuRe 70 Protein A Resin, 200 mL (17542402) gives Australian laboratories and bioprocess teams a high DBC protein A resin for efficient monoclonal antibody capture. John Morris Group supplies Cytiva chromatography products with local support to help match resin format, process scale and purification workflow to your application.
