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Syrris Gilson 271XL Feed Robot
Overview
The Reagent Injection Modules consist of a Gilson autosampler, RIM:Feed (Reagent Injection Module:Feed) and RIM:Loops (Reagent Injection Module:Loops).
Together they enable hundreds of compounds to be injected into the flow reactor under pressure, separated by a solvent analogous to bullets down the barrel of a machine gun. The Reagent Injection Modules can inject multiple reactions into the flowing stream in a fast serial fashion so that several reactions are in the system at a time.
The injection timing of up to four components per reaction is fully controlled by the software to ensure samples meet in the reactor(s) at the correct time.
Lists of reagents/substrates can be imported into the software from .csv files and their volume tracked during use enabling full resource management.
These modules are suited to the following applications: synthetic libraries, reagent screening, reaction optimisation, kinetic studies, degradation studies, logD screening etc.
Gilson GX-271: Industry standard, reliable autosampler capable of accessing 100s of substrates/reagents. This is modified with a custom coaxial needle to enable septum piercing and aspiration of air sensitive reagents. The deck can be configured by the customer to accept custom arrangements of vials and/or bottles.