CEM Fmoc-Ser(tBu)-OH (N-Fmoc-O-tert-butyl-serine) is a high-purity amino acid designed for peptide synthesis. Optimized ProTide resins with PEG and polystyrene core provide excellent swelling properties, enabling efficient synthesis of difficult peptides.
Product Features
- ProTide™ resins with ideal PEG and polystyrene core for enhanced peptide synthesis environment
- Incorporates Cl-TCP(Cl) and Cl-MPA universal linkers, eliminating the need for pre-loaded C-terminal amino acids
- C-terminal amino acid reacts with linker-chloride in the presence of potassium iodide (KI), N,N-diisopropylethylamine (DIEA), and microwave irradiation
- Automatic loading on Liberty Blue microwave peptide synthesizer using pre-programmed software methods
- Any amino acid can be loaded on the resins in 10 minutes
- Exhibits strong stability towards hydrolysis during storage and handling
- TCP(Cl) is hyperacid sensitive and produces protected peptides with 1% TFA/DCM
- Minimizes diketopiperazine and 3-(1-piperidinyl)alanine formation
- No longer need to purchase or store more than 20 different pre-loaded acid-linked resins
Key Advantages
- Automated high-temperature loading procedure completed in 10 minutes, compared to 24 hours at room temperature
- Avoids coupling reagents, reducing epimerization and dipeptide formation during loading
- Supports rapid and efficient peptide synthesis with high reproducibility
- Compatible with Liberty Blue microwave peptide synthesizers and other automated systems
Benefits
- Reduces synthesis time and increases peptide production efficiency
- Minimizes reagent use and waste, making workflows cost-effective
- Provides consistent, high-quality peptide yields for research and industrial applications
- Supports complex and difficult peptide sequences with reliability
- Enhances reproducibility and safety during peptide synthesis
Why Choose CEM Fmoc-Ser(tBu)-OH, Amino Acid, 1kg?
This amino acid provides a high-quality solution for peptide synthesis using universal ProTide resins, enabling fast, efficient, and reproducible results for research and industrial peptide synthesis applications.
