CEM Fmoc-Ile-OH Amino Acid (5 mmol, 5 pack) is a high-performance PEG-polystyrene ProTide™ resin designed for efficient peptide synthesis. Featuring an optimized PEG resin core with Cl-TCP(Cl) and Cl-MPA universal linkers, it provides excellent swelling properties and simplifies amino acid loading.
Product Features
- Optimized PEG-polystyrene core for ideal environment in difficult peptide synthesis
- Incorporates Cl-TCP(Cl) and Cl-MPA universal linkers, eliminating the need for pre-loaded C-terminal amino acids
- C-terminal amino acid reacts with linker-chloride using potassium iodide (KI), N,N-diisopropylethylamine (DIEA), and microwave irradiation
- Automated loading on Liberty Blue microwave peptide synthesizer with pre-programmed methods
- Strong swelling properties for consistent peptide synthesis
Key Advantages
- Automated, high-temperature loading procedure complete in 10 min, whereas room temperature may take up to 24 hours
- Avoids coupling reagents, eliminating epimerization and dipeptide formation during loading
- No longer need to buy/store > 20 different pre-loaded acid-linked resins
- Exhibits strong stability towards hydrolysis during storage and handling
- TCP(Cl) is hyperacid sensitive and produces protected peptides with 1% TFA/DCM
- Minimizes diketopiperazine and 3-(1-piperidinyl)alanine formation
Benefits
- Enables efficient, rapid amino acid loading on resins
- Reduces chemical waste and storage complexity
- Reliable, reproducible peptide synthesis environment
Why Choose CEM Fmoc-Ile-OH Amino Acid, 5 mmol, 5 Pack?
ProTide™ resins with Fmoc-Ile-OH simplify peptide synthesis by providing a versatile, stable, and high-performing resin suitable for automated microwave synthesis, reducing errors and enhancing workflow efficiency.
